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1

ACE2 gene variants may underlie interindividual variability and susceptibility to COVID-19 in the Italian population

Benetti, Elisa, Tita, Rossella, Spiga, Ottavia, Ciolfi, Andrea, Birolo, Giovanni, Bruselles, Alessandro, Doddato, Gabriella, Giliberti, Annarita, Marconi, Caterina, Musacchia, Francesco, Pippucci, Tom

Journal:

European Journal of Human Genetics

Year:

2020

File:

PDF, 2.09 MB

2020

2

On the mechanisms of bananin activity against severe acute respiratory syndrome coronavirus

Zai Wang, Jian-Dong Huang, Kin-Ling Wong, Pei-Gang Wang, Hao-Jie Zhang, Julian A. Tanner, Ottavia Spiga, Andrea Bernini, Bo-Jian Zheng, Neri Niccolai

Journal:

Year:

2011

Language:

english

File:

PDF, 477 KB

english, 2011

3

Interactive alkaptonuria database: investigating clinical data to improve patient care in a rare disease

Cicaloni, Vittoria, Spiga, Ottavia, Dimitri, Giovanna Maria, Maiocchi, Rebecca, Millucci, Lia, Giustarini, Daniela, Bernardini, Giulia, Bernini, Andrea, Marzocchi, Barbara, Braconi, Daniela, Santucci,

Journal:

The FASEB Journal

Year:

2019

Language:

english

File:

PDF, 962 KB

english, 2019

4

α2A adrenergic receptors highly expressed in mesoprefrontal dopamine neurons

Castelli, M. Paola, Spiga, Saturnino, Perra, Andrea, Madeddu, Camilla, Mulas, Giovanna, Ennas, M. Grazia, Gessa, Gian Luigi

Journal:

Year:

2016

Language:

english

File:

PDF, 2.16 MB

english, 2016

5

Groups satisfying a strong complement property

Detomi, Eloisa, Lucchini, Andrea, Moscatiello, Mariapia, Spiga, Pablo, Traustason, Gunnar

Journal:

Journal of Algebra

Year:

2019

Language:

english

File:

PDF, 387 KB

english, 2019

6

From in silico to in vitro: a trip to reveal flavonoid binding on the Rattus norvegicus Kir6.1 ATP-sensitive inward rectifier potassium channel

Trezza, Alfonso, Cicaloni, Vittoria, Porciatti, Piera, Langella, Andrea, Fusi, Fabio, Saponara, Simona, Spiga, Ottavia

Journal:

Year:

2018

Language:

english

File:

PDF, 30.21 MB

english, 2018

7

Machine learning application for development of a data-driven predictive model able to investigate quality of life scores in a rare disease

Spiga, Ottavia, Cicaloni, Vittoria, Fiorini, Cosimo, Trezza, Alfonso, Visibelli, Anna, Millucci, Lia, Bernardini, Giulia, Bernini, Andrea, Marzocchi, Barbara, Braconi, Daniela, Prischi, Filippo, Santu

Journal:

Orphanet Journal of Rare Diseases

Year:

2020

File:

PDF, 1.37 MB

2020

8

Probing protein surface accessibility with solvent and paramagnetic molecules

Andrea Bernini, Vincenzo Venditti, Ottavia Spiga, Neri Niccolai

Journal:

Progress in Nuclear Magnetic Resonance Spectroscopy

Year:

2009

Language:

english

File:

PDF, 571 KB

english, 2009

9

Effect of Upstream Turbine Tip Speed Variations on Downstream Turbine Performance

Ceccotti, Clio, Spiga, Andrea, Bartl, Jan, Sætran, Lars

Journal:

Energy Procedia

Year:

2016

Language:

english

File:

PDF, 943 KB

english, 2016

10

NMR studies of the inclusion complex between β-cyclodextrin and paroxetine

Andrea Bernini, Ottavia Spiga, Arianna Ciutti, Maria Scarselli, Giuseppe Bottoni, Paolo Mascagni, Neri Niccolai

Journal:

European Journal of Pharmaceutical Sciences

Year:

2004

Language:

english

File:

PDF, 162 KB

english, 2004

11

Prediction of quaternary assembly of SARS coronavirus peplomer

Andrea Bernini, Ottavia Spiga, Arianna Ciutti, Stefano Chiellini, Luisa Bracci, Xiyun Yan, Bojian Zheng, Jiandong Huang, Ming-Liang He, Huai-Dong Song, Pei Hao, Guoping Zhao, Neri Niccolai

Journal:

Biochemical and Biophysical Research Communications

Year:

2004

Language:

english

File:

PDF, 755 KB

english, 2004

12

HISTIDYL TAGS AND STRUCTURAL STABILIZATION OF LINEAR PEPTIDES

Spiga, Ottavia, Bernini, Andrea, Scarselli, Maria, Giovannoni, Leonardo, Laschi, Franco, Neri, Paolo, Bracci, Luisa, Lozzi, Luisa, Niccolai, Neri

Journal:

Spectroscopy Letters

Year:

2002

Language:

english

File:

PDF, 362 KB

english, 2002

13

Homogentisate 1,2-dioxygenase (HGD) gene variants, their analysis and genotype–phenotype correlations in the largest cohort of patients with AKU

Ascher, David B., Spiga, Ottavia, Sekelska, Martina, Pires, Douglas E. V., Bernini, Andrea, Tiezzi, Monica, Kralovicova, Jana, Borovska, Ivana, Soltysova, Andrea, Olsson, Birgitta, Galderisi, Silvia,

Journal:

European Journal of Human Genetics

Year:

2019

Language:

english

File:

PDF, 1.88 MB

english, 2019

14

Transient pockets as mediators of gas molecules routes inside proteins: the case study of dioxygen pathway in homogentisate 1,2-dioxygenase and its implication in Alkaptonuria development

Bernini, Andrea, Galderisi, Silvia, Spiga, Ottavia, Amarabom, Chukwudi Onyekachi, Santucci, Annalisa

Journal:

Computational Biology and Chemistry

Year:

2020

File:

PDF, 2.73 MB

2020

15

Probing the protein space for extending the detection of weak homology folds

Gullotto, Danilo, Nolassi, Mario Salvatore, Bernini, Andrea, Spiga, Ottavia, Niccolai, Neri

Journal:

Journal of Theoretical Biology

Year:

2013

Language:

english

File:

PDF, 714 KB

english, 2013

16

Characterization of transient currents in HfO2 capacitors in the short timescale

Christian Monzio Compagnoni, Alessandro S. Spinelli, Andrea Bianchini, Andrea L. Lacaita, Sabina Spiga, Marco Fanciulli

Journal:

Microelectronic Engineering

Year:

2006

Language:

english

File:

PDF, 120 KB

english, 2006

17

ROYAL ACADEMY OF MEDICINE IN IRELAND.

Gullotto, Danilo, Nolassi, Mario Salvatore, Bernini, Andrea, Spiga, Ottavia, Niccolai, Neri

Journal:

Year:

1897

Language:

english

File:

PDF, 451 KB

english, 1897

18

Immunohistochemical localization of atrial natriuretic factor and autoradiographic distribution of atrial natriuretic factor-binding sites in the brain of the cave salamander Hydromantes genei (Amphibia, Plethodontidae)

Maura Mathieu, Michele Trabucchi, Mauro Vallarino, Andrea Pedrazzi, Giuliana Serra, Saturnino Spiga, Hubert Vaudry

Journal:

The Journal of Comparative Neurology

Year:

2001

Language:

english

File:

PDF, 1.25 MB

english, 2001

19

NMR Studies of Protein Hydration and TEMPOL Accessibility

Neri Niccolai, Ottavia Spiga, Andrea Bernini, Maria Scarselli, Arianna Ciutti, Irene Fiaschi, Stefano Chiellini, Henriette Molinari, Piero A Temussi

Journal:

Journal of Molecular Biology

Year:

2003

Language:

english

File:

PDF, 1.61 MB

english, 2003

20

SPIE Proceedings [SPIE SPIE Astronomical Telescopes + Instrumentation - Edinburgh, United Kingdom (Sunday 26 June 2016)] Space Telescopes and Instrumentation 2016: Ultraviolet to Gamma Ray - Monte Carlo simulations of soft proton flares: testing the physics with XMM-Newton

den Herder, Jan-Willem A., Takahashi, Tadayuki, Bautz, Marshall, Fioretti, Valentina, Bulgarelli, Andrea, Malaguti, Giuseppe, Spiga, Daniele, Tiengo, Andrea

Year:

2016

Language:

english

File:

PDF, 1.49 MB

english, 2016

21

Peptide–protein interactions studied by surface plasmon and nuclear magnetic resonances

Ottavia Spiga, Andrea Bernini, Maria Scarselli, Arianna Ciutti, Luisa Bracci, Luisa Lozzi, Barbara Lelli, Daniela Di Maro, Duccio Calamandrei, Neri Niccolai

Journal:

Year:

2002

Language:

english

File:

PDF, 135 KB

english, 2002

22

Hot spot mapping of protein surfaces with TEMPOL: Bovine pancreatic RNase A as a model system

Niccolai, Neri, Morandi, Edoardo, Gardini, Simone, Costabile, Valentino, Spadaccini, Roberta, Crescenzi, Orlando, Picone, Delia, Spiga, Ottavia, Bernini, Andrea

Journal:

Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics

Year:

2017

Language:

english

File:

PDF, 1.48 MB

english, 2017

23

Hydration studies on the archaeal protein Sso7d using NMR measurements and MD simulations

Andrea Bernini, Ottavia Spiga, Roberto Consonni, Ivana Arosio, Paola Fusi, Simone Cirri, Annamaria Guagliardi, Neri Niccolai

Journal:

BMC Structural Biology

Year:

2011

Language:

english

File:

PDF, 896 KB

english, 2011

24

Structure–Function Paradigm in Human Myoglobin: How a Single-Residue Substitution Affects NO Reactivity at Low pO 2

Scorciapino, Mariano Andrea, Spiga, Enrico, Vezzoli, Alessandra, Mrakic-Sposta, Simona, Russo, Rosaria, Fink, Bruno, Casu, Mariano, Gussoni, Maristella, Ceccarelli, Matteo

Journal:

Journal of the American Chemical Society

Year:

2013

Language:

english

File:

PDF, 1.50 MB

english, 2013

25

Synthesis and Superpotent Anticancer Activity of Tubulysins Carrying Non-hydrolysable N-Substituents on Tubuvaline

Sani, Monica, Lazzari, Paolo, Folini, Marco, Spiga, Marco, Zuco, Valentina, De Cesare, Michelandrea, Manca, Ilaria, Dall'Angelo, Sergio, Frigerio, Massimo, Usai, Igor, Testa, Andrea, Zaffaroni, Nadia,

Journal:

Chemistry - A European Journal

Year:

2017

Language:

english

File:

PDF, 2.71 MB

english, 2017

26

Homogentisate 1,2-dioxygenase (HGD) gene variants, their analysis and genotype–phenotype correlations in the largest cohort of patients with AKU

Ascher, David B., Spiga, Ottavia, Sekelska, Martina, Pires, Douglas E. V., Bernini, Andrea, Tiezzi, Monica, Kralovicova, Jana, Borovska, Ivana, Soltysova, Andrea, Olsson, Birgitta, Galderisi, Silvia,

Journal:

European Journal of Human Genetics

Year:

2019

File:

PDF, 1.88 MB

2019

27

Groups satisfying a strong complement property

Detomi, Eloisa, Lucchini, Andrea, Moscatiello, Mariapia, Spiga, Pablo, Traustason, Gunnar

Journal:

Journal of Algebra

Year:

2019

File:

PDF, 387 KB

2019

28

The planimetric Grothoff's criteria by cardiac magnetic resonance can improve the specificity of left ventricular non-compaction diagnosis in thalassemia intermedia

Macaione, Francesca, Meloni, Antonella, Positano, Vincenzo, Pistoia, Laura, Barison, Andrea, Di Lisi, Daniele, Spasiano, Anna, Campisi, Saveria, Spiga, Alessandra, Righi, Riccardo, Novo, Giuseppina, N

Journal:

The International Journal of Cardiovascular Imaging

Year:

2020

Language:

english

File:

PDF, 877 KB

english, 2020

29

Structure and function correlations between the rat liver threonine deaminase and aminotransferases

Maria Scarselli, Maria Giuseppina Padula, Andrea Bernini, Ottavia Spiga, Arianna Ciutti, Roberto Leoncini, Daniela Vannoni, Enrico Marinello, Neri Niccolai

Journal:

Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics

Year:

2003

Language:

english

File:

PDF, 603 KB

english, 2003

30

A structural study of the optic nerve of Hydromantes genei

Spiga, Saturnino, Sabatini, Andrea, Siddi, Alessandra, Puddu, M. Cristina, Argiolas, Mauro, Serra, Giuliana P.

Journal:

Italian Journal of Zoology

Year:

2000

Language:

english

File:

PDF, 749 KB

english, 2000

31

A new integrated and interactive tool applicable to inborn errors of metabolism: Application to alkaptonuria

Spiga, Ottavia, Cicaloni, Vittoria, Zatkova, Andrea, Millucci, Lia, Bernardini, Giulia, Bernini, Andrea, Marzocchi, Barbara, Bianchini, Monica, Zugarini, Andrea, Rossi, Alberto, Zazzeri, Matteo, Trezz

Journal:

Computers in Biology and Medicine

Year:

2018

Language:

english

File:

PDF, 1.20 MB

english, 2018

32

NMR and MD Studies on the Interaction Between Ligand Peptides and α-Bungarotoxin

Andrea Bernini, Arianna Ciutti, Ottavia Spiga, Maria Scarselli, Samuel Klein, Stefano Vannetti, Luisa Bracci, Luisa Lozzi, Barbara Lelli, Chiara Falciani, Paolo Neri, Neri Niccolai

Journal:

Journal of Molecular Biology

Year:

2004

Language:

english

File:

PDF, 335 KB

english, 2004

33

[IEEE 2006 International Symposium on Industrial Embedded Systems - Antibes Juan-Les-Pins, France (2006.10.18-2006.10.20)] 2006 International Symposium on Industrial Embedded Systems - Exploiting Memory-Boundedness in Energy-Efficient Hard Real-Time Scheduling

Spiga, Marco, Spiga, Mattia, Alimonda, Andrea, Carta, Salvatore, Aymerich, Francesco, Acquaviva, Andrea

Year:

2006

Language:

english

File:

PDF, 1.62 MB

english, 2006

34

NMR studies of BPTI aggregation by using paramagnetic relaxation reagents

Andrea Bernini, Ottavia Spiga, Arianna Ciutti, Vincenzo Venditti, Filippo Prischi, Mariangela Governatori, Luisa Bracci, Barbara Lelli, Silvia Pileri, Mauro Botta, Alessandro Barge, Franco Laschi, Ner

Journal:

Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics

Year:

2006

Language:

english

File:

PDF, 399 KB

english, 2006

35

NMR Studies of Lysozyme Surface Accessibility by Using Different Paramagnetic Relaxation Probes

Bernini, Andrea, Spiga, Ottavia, Venditti, Vincenzo, Prischi, Filippo, Bracci, Luisa, Tong, Angela Pui-Ling, Wong, Wing-Tak, Niccolai, Neri

Journal:

Journal of the American Chemical Society

Year:

2006

Language:

english

File:

PDF, 104 KB

english, 2006

36

A structurally driven analysis of thiol reactivity in mammalian albumins

Ottavia Spiga, Domenico Summa, Simone Cirri, Andrea Bernini, Vincenzo Venditti, Matteo De Chiara, Raffaella Priora, Simona Frosali, Antonios Margaritis, Danila Di Giuseppe, Paolo Di Simplicio, Neri Ni

Journal:

Year:

2011

Language:

english

File:

PDF, 451 KB

english, 2011

37

Metal ion complexation and folding of linear peptides

Ottavia Spiga, Maria Scarselli, Andrea Bernini, Arianna Ciutti, Leonardo Giovannoni, Franco Laschi, Luisa Bracci, Neri Niccolai

Journal:

Biophysical Chemistry

Year:

2002

Language:

english

File:

PDF, 282 KB

english, 2002

38

Boosting phagocytosis and anti-inflammatory phenotype in microglia mediates neuroprotection by PPARγ agonist MDG548 in Parkinson's disease.

Lecca, Daniela, Janda, Elzbieta, Mulas, Giovanna, Diana, Andrea, Martino, Concetta, Angius, Fabrizio, Spolitu, Stefano, Antonietta Casu, M, Simbula, Gabriella, Boi, Laura, Batetta, Barbara, Spiga, Sat

Journal:

British Journal of Pharmacology

Year:

2018

Language:

english

File:

PDF, 688 KB

english, 2018

39

Homogentisic acid induces aggregation and fibrillation of amyloidogenic proteins

Braconi, Daniela, Millucci, Lia, Bernini, Andrea, Spiga, Ottavia, Lupetti, Pietro, Marzocchi, Barbara, Niccolai, Neri, Bernardini, Giulia, Santucci, Annalisa

Journal:

Biochimica et Biophysica Acta (BBA) - General Subjects

Year:

2016

Language:

english

File:

PDF, 1.14 MB

english, 2016

40

Exploiting private and commercial clouds to generate on-demand CMS computing facilities with DODAS

Spiga, Daniele, Antonacci, Marica, Boccali, Tommaso, Ceccanti, Andrea, Ciangottini, Diego, Di Maria, Riccardo, Donvito, Giacinto, Duma, Cristina, Gaido, Luciano, LÃ³pez GarcÃa, Ãlvaro, Palacio Hoz,

Journal:

EPJ Web of Conferences

Year:

2019

File:

PDF, 1.01 MB

2019

41

AKUImg: A database of cartilage images of Alkaptonuria patients

Rossi, Alberto, Giacomini, Giorgia, Cicaloni, Vittoria, Galderisi, Silvia, Milella, Maria Serena, Bernini, Andrea, Millucci, Lia, Spiga, Ottavia, Bianchini, Monica, Santucci, Annalisa

Journal:

Computers in Biology and Medicine

Year:

2020

File:

PDF, 3.36 MB

2020

42

Molecular modelling of S1 and S2 subunits of SARS coronavirus spike glycoprotein

Ottavia Spiga, Andrea Bernini, Arianna Ciutti, Stefano Chiellini, Nicola Menciassi, Francesca Finetti, Vincenza Causarono, Francesca Anselmi, Filippo Prischi, Neri Niccolai

Journal:

Biochemical and Biophysical Research Communications

Year:

2003

Language:

english

File:

PDF, 592 KB

english, 2003

43

MD and NMR studies of α-bungarotoxin surface accessibility

Vincenzo Venditti, Andrea Bernini, Alfonso De Simone, Ottavia Spiga, Filippo Prischi, Neri Niccolai

Journal:

Biochemical and Biophysical Research Communications

Year:

2007

Language:

english

File:

PDF, 197 KB

english, 2007

44

Maximal subgroups of finite groups avoiding the elements of a generating set

Lucchini, Andrea, Spiga, Pablo

Journal:

Monatshefte für Mathematik

Year:

2016

Language:

english

File:

PDF, 538 KB

english, 2016

45

NMR Structure of α-Bungarotoxin Free and Bound to a Mimotope of the Nicotinic Acetylcholine Receptor †

Scarselli, Maria, Spiga, Ottavia, Ciutti, Arianna, Bernini, Andrea, Bracci, Luisa, Lelli, Barbara, Lozzi, Luisa, Calamandrei, Duccio, Di Maro, Daniela, Klein, Samuel, Niccolai, Neri

Journal:

Year:

2002

Language:

english

File:

PDF, 327 KB

english, 2002

46

Structure and interface bonding of GeO[sub 2]∕Ge∕In[sub 0.15]Ga[sub 0.85]As heterostructures

Molle, Alessandro, Spiga, Sabina, Andreozzi, Andrea, Fanciulli, Marco, Brammertz, Guy, Meuris, Marc

Journal:

Applied Physics Letters

Year:

2008

Language:

english

File:

PDF, 579 KB

english, 2008

47

[IEEE 2017 IEEE International Parallel and Distributed Processing Symposium Workshops (IPDPSW) - Orlando / Buena Vista, FL, USA (2017.5.29-2017.6.2)] 2017 IEEE International Parallel and Distributed Processing Symposium Workshops (IPDPSW) - Design of an Energy Aware Petaflops Class High Performance Cluster Based on Power Architecture

Ahmad, Wissam Abu, Bartolini, Andrea, Beneventi, Francesco, Benini, Luca, Borghesi, Andrea, Cicala, Marco, Forestieri, Privato, Gianfreda, Cosimo, Gregori, Daniele, Libri, Antonio, Spiga, Filippo, Tin

Year:

2017

Language:

english

File:

PDF, 555 KB

english, 2017

48

Toward a generalized computational workflow for exploiting transient pockets as new targets for small molecule stabilizers: application to the homogentisate 1,2-dioxygenase mutants at the base of rare disease Alkaptonuria

Bernini, Andrea, Galderisi, Silvia, Spiga, Ottavia, Bernardini, Giulia, Niccolai, Neri, Manetti, Fabrizio, Santucci, Annalisa

Journal:

Computational Biology and Chemistry

Year:

2017

Language:

english

File:

PDF, 1.95 MB

english, 2017

49

A REMARK ON THE PERMUTATION REPRESENTATIONS AFFORDED BY THE EMBEDDINGS OF IN

GUEST, SIMON, PREVITALI, ANDREA, SPIGA, PABLO

Journal:

Bulletin of the Australian Mathematical Society

Year:

2014

Language:

english

File:

PDF, 219 KB

english, 2014

50

Searching for protein binding sites from Molecular Dynamics simulations and paramagnetic fragment-based NMR studies

Bernini, Andrea, Henrici De Angelis, Lucia, Morandi, Edoardo, Spiga, Ottavia, Santucci, Annalisa, Assfalg, Michael, Molinari, Henriette, Pillozzi, Serena, Arcangeli, Annarosa, Niccolai, Neri

Journal:

Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics

Year:

2014

Language:

english

File:

PDF, 912 KB

english, 2014

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